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Pancreatic ductal compartment contributes to regeneration of new endocrine and acinar cells.

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The pancreas originates from two restricted domains of the foregut endoderm.

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Pancreatic Cancer

Pancreatic intraepithelial neoplasia (PanIN) is the most common precursor to pancreatic ductal adenocarcinoma.

Our Research

Esni lab researchers study the genetics of pancreatic cancer and diabetes. In particular, we are interested in determining the role of hypoxia during pancreatic cancer progression as well as studying regeneration in the adult mouse pancreas.